When a top-secret weapon is stolen from a U.S. defense contractor, CIA agent Colin Glass is paired with FBI agent Bill Goodman to investigate. Their partnership gets off to a rocky start, but they soon realize their opposing viewpoints may be their greatest asset.

When a known smuggler is flagged at the New York border with unidentified cargo, Colin and Bill head upstate to track. To find this smuggler, they must enlist the help of a foreign intelligence officer looking to defect.

When a deeply embedded U.S. intelligence officer is detained in Hong Kong, Nikki insists on traveling there to bring him home but her cover is blown.

When a wanted Belarusian national is discovered posing as an expecting father, Colin and Bill work to expose an international illegal baby smuggling ring. Meanwhile, Bill worries about his father's health back home.